New program aims to help breast cancer patients talk about what matters most
NCT ID NCT06795529
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a five-session palliative care program called TARGET-PC for people with metastatic breast cancer and their caregivers. The goal is to help patients talk with their doctors about their goals and values for care, and to have those preferences documented. The study will compare this program to enhanced usual care in 400 patients across multiple sites.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- palliative care program (TARGET-PC)
- What this could lead to
- If successful, this could show that a structured palliative care program helps patients with metastatic breast cancer have earlier and better conversations with their doctors about what matters most in their care.
- What could go wrong
- This is a behavioral intervention trial, not a drug study, so it won't directly treat the cancer. The benefits may be modest and depend on how well patients and clinicians engage with the program.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 400 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Oct 2025
- Expected to finish
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Mar 2030
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Patient Inclusion Criteria: * age ≥18 years * diagnosed with metastatic breast cancer * within 8 weeks of the oncology visit at which they were identified as having an eligible Epic EOL Care Index (≥ 15) * functioning independently per an Eastern Cooperative Oncology Group performance status ≤2 * receiving their cancer care at one of the participating institutions * able to complete questionnaires in English or Spanish Patient Exclusion Criteria: * received outpatient palliative care visit within the last six months * enrolled in hospice services * diagnosed with a comorbid condition that impairs their ability to understand study procedures and/or consent for the trial as per the report of the oncology clinician(s) Caregiver Inclusion Criteria: * age ≥18 years * identified by the patient as a family member or friend who is primarily involved in their care * able to complete questionnaires in English or Spanish
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
3 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Duke University
RECRUITINGDurham, North Carolina, 54677, United States
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Massachusetts General Hospital
RECRUITINGBoston, Massachusetts, 02465, United States
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University of Pennsylvania
RECRUITINGPhiladelphia, Pennsylvania, 46205, United States
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Other studies related to the condition(s) this trial covers.
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- Can a blood test reveal when breast cancer treatment stops working?
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- Can a Two-Drug combo outsmart resistant breast and ovarian cancers?