Which palliative care approach boosts quality of life in advanced lung cancer?
NCT ID NCT03337399
First seen Aug 03, 2026 · Last updated Aug 04, 2026 · Updated 1 time
Summary
This study looks at two ways of delivering palliative care—specialized support to ease symptoms and stress—for people recently diagnosed with advanced lung cancer. One approach starts with basic palliative care and adds more if needed, while the other provides full palliative care right away. The goal is to see which approach better improves patients' quality of life and helps them discuss their care preferences with their doctors.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Palliative care delivered in two different ways: stepped (starting with basic support and adding more if needed) versus early integrated (full palliative care from the start)
- What this could lead to
- If one approach proves better, it could point toward a standard way to deliver palliative care that improves quality of life for people with advanced lung cancer.
- What could go wrong
- The trial is early and results may not apply to all patients. Palliative care aims to ease symptoms, but it cannot cure the cancer, and individual experiences may vary.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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507 people
The number who actually took part.
- Started
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Feb 2018
- Finished
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Dec 2023
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Diagnosed with advanced non-small cell lung cancer, small cell lung cancer, or mesothelioma, being treated with non-curative intent, and informed of advanced disease within the prior twelve weeks * Eastern Cooperative Oncology Group (ECOG) Performance Status from 0 (asymptomatic) to 2 (symptomatic and in bed \<50% of the day) * The ability to read and respond to questions in English or Spanish * Primary cancer care at one of the three participating sites * Age \> 18 years Exclusion Criteria: * Already receiving outpatient PC or hospice services * Cognitive or psychiatric conditions as determined by the treating oncologist to prohibit study consent or participation
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Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Duke University
Durham, North Carolina, 27710, United States
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
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