Talking away the pain: new therapy targets fear of facial pain

NCT ID NCT07123233

Recruiting now Symptom relief Sponsor: Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta Source: ClinicalTrials.gov ↗

First seen Nov 18, 2025 · Last updated Jun 15, 2026 · Updated 25 times

Summary

This study tests a type of talk therapy called Pain Reprocessing Therapy (PRT) for people with chronic face pain that has no clear physical cause. The goal is to see if changing how the brain processes pain can lower pain intensity and improve quality of life. Sixty adults will be randomly assigned to either PRT or standard care, and followed for a year.

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Contacts and locations

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Study contacts

Contact

Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Fondazione IRCCS Istituto Neurologico Carlo Besta
RECRUITING

Milan, 20133, Italy

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

Chronic Pain Nociplastic Pain persistent idiopathic facial pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC PRIMARY OROFACIAL PAIN (CPOP) PERSISTENT IDIOPATHIC FACIAL PAIN (PIFP)