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New painkiller cocktail cuts opioid use after gallbladder surgery

NCT ID NCT07388251

First seen Feb 05, 2026 · Last updated Jun 21, 2026 · Updated 17 times

Summary

This study looked at whether adding dexmedetomidine to a common numbing medicine (bupivacaine) could improve pain control after laparoscopic gallbladder removal. Thirty adults having elective surgery were randomly assigned to receive either the combo or bupivacaine alone, sprayed inside the belly at the end of surgery. The combo group reported less pain in the first 24 hours, waited longer before needing extra pain relief, and used fewer opioids, with no serious side effects.

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Contacts and locations

Locations

  • intensive care unit Department, Ain Shams University Hospital

    Cairo, Cairo Governorate, 11517, Egypt

Conditions

The condition(s) this trial relates to.

cholelithiasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.