New nerve block could ease pain of broken ribs without opioids
NCT ID NCT07493473
First seen Jun 26, 2026 · Last updated Sep 04, 2026 · Updated 3 times
Summary
This study tests two different nerve block methods to control pain in people with multiple broken ribs. The goal is to see which technique provides better pain relief, helps patients breathe deeper, and shortens hospital stays. Thirty-six adults with at least two rib fractures will receive either a parascapular sub-iliocostalis plane block or a thoracic paravertebral block, both using the numbing medicine bupivacaine.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- nerve block (local anesthetic bupivacaine)
- What this could lead to
- If successful, this could offer a safer, effective pain relief option for rib fracture patients, reducing opioid use and complications like pneumonia.
- What could go wrong
- This is a small, early-phase study with only 36 participants, so results may not apply broadly. Both procedures carry risks like bleeding or infection.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 36 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
May 2025
- Expected to finish
-
Jan 2027
An estimate. End dates often move.
- Lead sponsor
-
A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
21 to 60 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patient written informed consent. * ASA I to III. * Age 21-60 years old. * Gender: Both. * BMI \< 35 Kg/M2. * Accepted mental state of the patient. * Patient with unilateral multiple rib fractures (≥2 fractures) Exclusion Criteria: * Any trauma in the patient that interfere with the positioning of patients for block. * Patients who needed mechanical ventilation before or during the study. * Patients with associated head trauma. * Patient with hemodynamic instability and need inotropic support. • Patient with abbreviated injury scale (AIS) in extremity more than 2 (10) * Pathological coagulopathy. * Infection at the injection site. * Disturbed conscious level. * An allergy to local anesthetics or any used drugs in this study. * Pregnancy.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Discitis of thoracic region are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
1 site. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
Zagazig university
RECRUITINGZagazig, Sharqia Province, 44111, Egypt