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Laser pain relief mystery: study to probe nerve changes in burn scars

NCT ID NCT04364217

First seen Jan 04, 2026 · Last updated Jun 19, 2026 · Updated 26 times

Summary

This study was designed to understand why fractional CO2 laser treatment reduces pain and itch in hypertrophic burn scars. Researchers planned to take small skin samples before and after laser treatment and look at nerve density and shape under a microscope. They also planned to track patients' symptoms using a standard questionnaire. However, the study was withdrawn before any participants were enrolled.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Fractional CO2 laser (device)

Conditions

The condition(s) this trial relates to.

Cicatrix, Hypertrophic Pain Pruritus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.