New study tests safer pain control for High-Risk amputation patients
NCT ID NCT07640516
First seen Jun 14, 2026 · Last updated Jun 19, 2026 · Updated 1 time
Summary
This study compares two drugs, dexmedetomidine and fentanyl, when added to a standard numbing medicine (bupivacaine) for nerve blocks in high-risk patients having an above-knee amputation. The goal is to see which provides better pain control during and after surgery, and whether it reduces the need for additional morphine. The trial plans to enroll 64 adults with serious heart or lung conditions.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for ABOVE KNEE AMPUTATION are added.
Genom att skicka in godkänner du våra Användarvillkor
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
Genom att skicka in godkänner du våra Användarvillkor
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
KasrELainiH
Cairo, Egypt
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Dexmedetomidine and fentanyl (added to bupivacaine for nerve block)
What this could lead to
If it works, this could point toward a better way to manage pain during and after above-knee amputation in high-risk patients, possibly reducing the need for strong opioids like morphine.
What could go wrong
This is a small, early-stage trial with only 64 participants, so results may not apply to everyone. The study is not yet recruiting, and it focuses on pain control, not curing the underlying condition.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.