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New pain combo could cut opioid use after stoma surgery

NCT ID NCT07368075

Symptom relief Sponsor: Sahiwal medical college sahiwal Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tested two different drug combinations for pain relief after stoma reversal surgery. 86 adults received either ropivacaine plus dexamethasone or ropivacaine plus dexmedetomidine in a nerve block. The goal was to see which combination provides longer pain relief and reduces the need for opioids. The trial is already completed.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Ropivacaine plus dexamethasone or ropivacaine plus dexmedetomidine
What this could lead to
If successful, this could point to a better way to manage pain after abdominal surgery, reducing the need for opioids and their side effects.
What could go wrong
This is a small, completed trial with only 86 participants, so results may not apply to everyone. The study compares two existing drugs, so no new treatment is being developed.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2/3

Runs two stages together: whether the treatment works, then large-scale confirmation.

Participants

86 people

The number who actually took part.

Started

Jul 2024

Finished

Jan 2026

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 60 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age limit: 18-60 years 2. Gender of patient i.e., male or female. 3. Patients listed for abdominal surgeries 4. American Society of Anesthesiologists (ASA) the status of I or II Exclusion Criteria: 1. Patients with history of drug allergy. 2. Patients with liver disease, kidney disease, cardiac disease or sickle cell anemia,severe preeclampsia CNS disorder on history. Clinical and laboratory assessment 3. American Society of Anesthesiologists (ASA status III or IV) 4. Patients with morbid obesity 5, Raynaud's disease 6\. Patients on adrenoceptor agonists or antagonists or narcotics before the operation

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Conditions

The condition(s) this trial relates to.

Bradycardia hypotensive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Bradycardia Hypotension, controlled Opioid sparing anaesthesia Post operative analgesia Stoma reversal procedure

Contacts and locations

Locations

  • Sahiwal Medical College

    Sāhīwāl, Punjab Province, 57000, Pakistan

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