Nerve block may reduce opioid use after stomach surgery
NCT ID NCT07634731
First seen Jun 25, 2026 · Last updated Sep 10, 2026 · Updated 4 times
Summary
This study compared two methods of pain control after open stomach surgery: a nerve block (rectus sheath block) using bupivacaine versus standard epidural pain relief. Sixty adults scheduled for elective open gastrectomy were randomly assigned to one of the two groups. The researchers measured pain levels and the amount of opioid painkillers needed in the first 72 hours after surgery, as well as recovery of bowel function.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- bupivacaine
- What this could lead to
- If successful, this could offer a safer, opioid-sparing pain management option for patients undergoing open stomach surgery.
- What could go wrong
- This is a small, completed trial with only 60 participants. Results may not apply to all patients or surgeries, and the nerve block may not work as well as standard epidural pain relief.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
60 people
The number who actually took part.
- Started
-
Oct 2021
- Finished
-
Dec 2024
- Lead sponsor
-
A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * (ASA) Grades I to III. * all adult patients (≥18 years) scheduled for elective open gastrectomy Exclusion Criteria: * those requiring acute gastric surgery, * individuals with known bupivacaine allergies * and patients who declined analgesia via RSB catheters and continuous bupivacaine infusions.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Bilateral rectus sheath block are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Riga East Clinical University Hospital
Riga, Riga, 1039, Latvia
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a personalized menu keep cancer patients stronger through chemotherapy?
- Nerve-Block procedure tested against severe pancreatic and stomach cancer pain
- Robotic surgery vs standard approaches: does the platform change cancer outcomes?
- Can a direct hit to tumors make immunotherapy work better?
- New antibody aims to preserve immune checkpoint while fighting cancer
- Engineered immune cells target two markers on Hard-to-Treat tumors