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New pain block study aims to ease recovery after major abdominal surgery

NCT ID NCT07055438

Symptom relief Sponsor: Kasr El Aini Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested two different ultrasound-guided nerve blocks to control pain after upper abdominal surgeries like Whipple or total gastrectomy. Forty adults received either a rectus sheath block or an external oblique intercostal plane block with bupivacaine. The goal was to see which block delays the need for rescue pain medication and reduces overall pain scores.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
bupivacaine
What this could lead to
If one block works better, it could lead to improved pain management after major abdominal surgery, reducing the need for strong painkillers.
What could go wrong
This is a small, completed study with only 40 patients, so results may not apply to everyone. The blocks are for short-term pain only and do not treat the underlying condition.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

40 people

The number who actually took part.

Started

Jul 2025

Finished

Nov 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age from 18 to 65 Years * Both sexes. * American Society of Anesthesiologists (ASA) physical status II, III. * Patients who will undergo upper abdominal surgeries (Whipple operation, total gastrectomy). Exclusion Criteria: * Coagulation disorders. * Abdominal surgery history. * Infection in the block application area. * Chronic opioid use. * Local anesthetic (LA) allergy. * Pregnancy. * BMI ≥35 kg/m2. * Severe cardiovascular problems. * Diabetic neuropathy. * Complicated surgeries with massive blood loss and hemodynamic instability.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Post operative analgesia

Contacts and locations

Locations

  • Kasr El Ainy

    Cairo, Egypt

  • National Cancer institute

    Cairo, Egypt

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