New pain block combo may speed heart surgery recovery
NCT ID NCT07304635
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether adding a second nerve block to a standard one can better control pain after heart surgery. Forty-two adults having elective heart surgery through a breastbone incision received either one or two nerve blocks. The goal was to see if the combination reduces pain, the need for extra painkillers, and the risk of confusion after surgery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- bupivacaine
- What this could lead to
- If successful, this could show that adding a second nerve block provides better pain control and faster recovery after heart surgery.
- What could go wrong
- This is a small, early-stage study with only 42 participants, so results may not apply to everyone. The added block may not improve pain or could increase risks.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
42 people
The number who actually took part.
- Started
-
Aug 2024
- Finished
-
Jul 2025
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 80 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria * Patients scheduled for elective cardiac surgery via median sternotomy under the ERACS protocol * Age between 18 and 80 years * ASA physical status II-III * Body Mass Index (BMI) between 18 and 35 kg/m² * No cognitive impairment (able to cooperate and follow commands) * No history of chronic pain or regular analgesic use * Provided written informed consent after detailed explanation of the study Exclusion Criteria * Age \< 18 years or \> 80 years * ASA physical status ≥ IV * Emergency surgery * Pregnant or breastfeeding women * Redo coronary artery bypass surgery * Pre-existing cognitive disorder or psychiatric illness affecting pain or delirium evaluation * Infection or skin lesion at the injection site * Known allergy or hypersensitivity to local anesthetics (bupivacaine or amide type) * Chronic pain or opioid use prior to surgery * Unwillingness to participate or withdrawal of consent at any stage
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Postoperative delirium are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Ankara University Faculty of Medicine
Ankara, 06230, Turkey (Türkiye)
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a common anesthetic stop Post-Surgery delirium in the elderly?
- Can a Pre-Surgery nerve block stop years of chest pain after heart surgery?
- Two sedatives, one question: can remimazolam shield the brain during aortic arch surgery?
- Can a forehead light sensor spot hidden brain oxygen drops during carotid surgery?
- Can a common sedative added to spinal anesthesia keep older minds clear after hip surgery?
- Could a sleep drug shield older hearts from post-surgery delirium?