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New pain block study for shoulder surgery: does the expensive version work better?

NCT ID NCT05900427

Symptom relief Sponsor: Johnny K. Lee Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early This study
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Aug 07, 2026 · Updated 2 times

Summary

This study looked at two different nerve blocks to manage pain after shoulder replacement surgery. One group received a standard painkiller (bupivacaine), while the other got a mix that included a longer-acting version (liposomal bupivacaine). The goal was to see which approach led to better pain control and less need for opioids in the days after surgery. The study was stopped early and enrolled 78 adults aged 18-90.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

78 people

The number who actually took part.

Started

Oct 2023

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 90 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Subject ages 18-90 years old * Male or Female subjects * Weight ≥ 60 kg. * Must be able to consent in English Exclusion Criteria: * Ages: \<18 and \>90 * Weight \< 60 kg * Multiple surgeries during one hospital stay * Emergency surgery * Allergy or any contraindication to local anesthetics used in trial. * Pregnancy * Contraindicated for use of liposomal bupivacaine * Severe liver/kidney disease * Defined as a diagnosis of end-stage renal disease (ESRD) defined as being on dialysis * Subject who received another local anesthetic block prior to the interscalene block. * Unable to consent in English

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Reverse total shoulder arthroplasty Total shoulder arthroplasty

Contacts and locations

Locations

  • NorthShore University HealthSystem

    Skokie, Illinois, 60076, United States

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