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Smart oxygen monitoring may reduce lung injury during surgery

NCT ID NCT07359833

First seen Jan 23, 2026 · Last updated Jun 23, 2026 · Updated 20 times

Summary

This study tested a new monitoring tool called the Oxygen Reserve Index (ORi) to help doctors give just the right amount of oxygen during lung surgery. Sixty adults having lung surgery with one-lung ventilation were randomly assigned to either ORi-guided oxygen management or standard care. The goal was to see if ORi guidance could lower oxygen exposure and reduce markers of oxidative stress and postoperative complications.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Gazi University

    Ankara, 06560, Turkey (Türkiye)

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Oxygen Reserve Index (ORi)-guided oxygen titration (device)

What this could lead to

If successful, this approach could help reduce oxygen-related lung injury during lung surgery, potentially leading to fewer breathing complications after surgery.

What could go wrong

This is a small, completed study with only 60 participants. The findings may not apply to all patients or surgeries, and the benefits of ORi guidance remain uncertain without larger trials.

Conditions

The condition(s) this trial relates to.

Hyperoxia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.