Metabolic clues: could your Body's energy use predict ovarian cancer outcomes?
NCT ID NCT07764133
First seen Aug 13, 2026 · Last updated Aug 18, 2026 · Updated 3 times
Summary
This study investigates whether measuring whole-body metabolism—how the body uses energy—can reflect the metabolic changes in ovarian tumors and predict how well patients respond to chemotherapy. Researchers will measure resting metabolic rate and other metabolic markers in women with suspected epithelial ovarian cancer before and during treatment. The goal is to find non-invasive ways to understand tumor metabolism and potentially identify new targets to restore chemotherapy sensitivity.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to a non-invasive way to predict how well ovarian cancer responds to chemotherapy, potentially guiding more personalized treatment plans.
- What could go wrong
- This is an early-stage observational study with a small number of participants. It may not establish a clear link, and findings may not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
About 50 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
May 2026
- Expected to finish
-
May 2028
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients with ovarian cancer receiving care at the study institution will be recruited for participation. Potential participants will be identified through their treating physicians and/or clinical care teams during routine clinical encounters, as well as through review of medical records for eligibility. The study population will include adults with ovarian cancer who are undergoing standard-of-care treatment, including surgery and/or chemotherapy, and who meet the study inclusion criteria. Participants will be followed prospectively to assess whole-body metabolic activity, tumor metabolic characteristics, and treatment-related outcomes. Efforts will be made to enroll a diverse group of participants representative of the patient population served by the institution.
- Ages
-
18 years and older
- Sex
-
Female participants only
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Women 2. Age \>18 years 3. Suspected of having epithelial ovarian cancer by the provider 4. No prior cytotoxic therapy for ovarian cancer 5. Surgical debulking is planned 6. ECOG performance status 0-1 Exclusion Criteria: 1. Inability to provide voluntary informed consent 2. Received medical intervention for adverse effects of chemotherapy 3. Circumstances and/or medical conditions that would limit compliance with study requirements and protocol, as determined by the principal investigators. 4. Poorly controlled diabetes, hemoglobin A1C ≥9%
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Epithelial ovarian cancer are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
1 site. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
University of Tennessee Medical Center - Knoxville
RECRUITINGKnoxville, Tennessee, 37920, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a Patient's own immune cells fight ovarian cancer?
- Ovarian Cancer's spread: scientists probe abdominal fluid for clues
- Mapping the DNA test that decides who gets PARP inhibitors
- Can inhaled manganese make ovarian cancer immunotherapy hit harder?
- Can a new drug combo keep ovarian cancer from coming back?
- Can a new imaging tracer light up ovarian cancer cells?