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Hands-On therapy may offer Drug-Free relief for chronic heartburn
NCT ID NCT06317675
First seen Jul 07, 2026 · Last updated Jul 08, 2026 · Updated 1 time
Summary
This study investigates whether osteopathic manipulative treatment (OMT) — a form of hands-on manual therapy — can reduce symptoms like heartburn and regurgitation in people with gastro-oesophageal reflux disease (GERD). The trial includes 26 adults who have had symptoms for at least three months and currently use acid-reducing medications. Researchers will measure changes in symptom severity and medication use over the study period.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Osteopathic manipulative treatment (manual therapy)
- What this could lead to
- If effective, this drug-free approach could help manage GERD symptoms and reduce reliance on acid-reducing medications.
- What could go wrong
- This is a small, early-phase trial with only 26 participants, so results may not apply broadly. The treatment may provide no benefit over standard care.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 2
Tests whether the treatment actually works, and watches for side effects, in a larger group.
- Participants
-
26 people
The number who actually took part.
- Started
-
Feb 2024
- Finished
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Jan 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Retrosternal burning sensation and/or regurgitation * Diagnosis of reflux with any methodology * Duration of symptoms for more than 3 months * Taking short or long-term proton pump inhibitors (as needed, treatment start date and expected end date, mg, drug name) * With or without esophagitis * With or without hiatal hernia * With or without helicobacter pylori * GERDQ questionnaire \> 8 points Exclusion Criteria: * neoplastic pathologies * patients who have undergone surgery for GERD * systemic pathologies (rheumatic, infectious conditions, feverish state, vascular alterations, endocrine diseases including diabetes, metabolic and neoplastic syndromes), * patients already undergoing manipulative therapy for reflux * patients with active gastric ulcers * congenital or acquired immune diseases * allergic state of any kind * pregnancy * use of intrauterine device * patients undergoing corticosteroid therapy * patients already subjected to manual/respiratory therapy in the last 3 months
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
CTFO
Saronno, Varese, 21047, Italy
More trials for these conditions
Other studies related to the condition(s) this trial covers.