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Finger in mouth could cure dry eyes? small study tests odd technique

NCT ID NCT07632183

Symptom relief Sponsor: Edward Via Virginia College of Osteopathic Medicine Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study tests whether a specific hands-on technique inside the mouth can increase tear production in healthy adults aged 18-45. Thirty volunteers will have their tears measured before and after the procedure, with follow-up visits at 2 days and 1 week. The goal is to see if this simple, non-invasive method could help people with dry eyes.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
sphenopalatine ganglion release (manual manipulation)
What this could lead to
If it works, this could offer a non-drug way to help people with dry eyes produce more tears.
What could go wrong
This is a very small pilot study with only 30 healthy volunteers, not patients with dry eye. Results may not apply to the general population or lead to a proven treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 30 people

The number the study aims to enrol. It can still change while the study runs.

Started

Oct 2024

Expected to finish

Jun 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 45 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * age 18-45 * 1st- 4th year medical students, faculty and staff volunteers at specific College of Osteopathic medicine campus Exclusion Criteria: * volunteers who have had ophthalmologic surgery * diagnosis of dry eye syndrome * diagnosis of temporomandibular joint disease * individuals who are greater than 45 years of age.

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Conditions

The condition(s) this trial relates to.

excessive tearing Lacerations

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Increased production of tears

Contacts and locations

Locations

  • VCOM- Carolinas Campus

    Spartanburg, South Carolina, 29303, United States