Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

New bone graft shows promise in neck fusion surgery

NCT ID NCT00942045

Disease control Sponsor: NuVasive Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at a product called Osteocel Plus used during neck fusion surgery for people with degenerative disc disease. The goal was to see how well the bones fused together and how safe the product was. 182 adults were followed for 24 months after surgery. The results were compared to older data from other bone graft materials.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

182 people

The number who actually took part.

Start date

Feb 2009

Finished

Oct 2012

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Existing clinic patients

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Persistent neck and/or arm pain unresponsive to conservative treatment for at least 6 weeks, unless clinically indicated sooner 2. Indicated for anterior fusion at one or two contiguous cervical levels (C3 to T1) 3. Objective evidence of primary diagnosis must be confirmed by appropriate imaging studies 4. 18-70 years of age at the date of written informed consent 5. Able to undergo surgery based on physical exam, medical history and surgeon judgment 6. Expected to survive at least 2 years beyond surgery 7. Willing and able to return for post-treatment exams according to the follow-up called for in the protocol 8. Signed and dated Informed Consent Form Exclusion Criteria: 1. Patient has a mental or physical condition that would limit the ability to comply with study requirements 2. Cervical spine abnormality requiring treatment at more than two levels 3. Systemic or local infection; active or latent 4. Previous failed fusion at the operative level 5. Diseases that significantly inhibit bone healing (osteoporosis, metabolic bone disease, uncontrolled diabetes, dialysis dependent renal failure, symptomatic liver disease) 6. Undergoing chemotherapy or radiation treatment, or chronic use of steroids (defined as more than 6 weeks of steroid use within 12 months of surgery, other than episodic use or inhaled corticosteroids) 7. Pregnant, or plans to become pregnant during the study 8. Subject is a prisoner 9. Involvement in active litigation relating to the spine (worker's compensation claim is allowed if it is not contended) 10. A significant general illness (e.g., HIV, active metastatic cancer of any type) is present; subject is immunocompromised or is being treated with immunosuppressive agents that decrease the probability of survival to the two-year endpoint of the study 11. Participating in another clinical study at any time during the study participation that would confound study data

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Degenerative disc disease in cervical spine are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

cervical disk degenerative disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Degenerative disc disease in cervical spine

Contacts and locations

Locations

  • Buffalo Spine Surgery, Kenmore Mercy

    Lockport, New York, 14094, United States

  • Columbia Orthopaedic Group, Boone Hospital Center

    Columbia, Missouri, 65201, United States

  • Duke University Medical Center

    Durham, North Carolina, 27708, United States

  • Hinsdale Orthopaedic Associates, Provena Saint Joseph Medical Center

    Joliet, Illinois, 60435, United States

  • Indiana Center for NeuroSurgery, Indiana Surgery Center East

    Indianopolis, Indiana, 46219, United States

  • NWREI (for Ortho Montana)

    Billings, Montana, 59101, United States

  • Pinnacle Orthopaedics, Wellstone Kennestone Hospital

    Marietta, Georgia, 30060, United States

  • Shiley Center for Orthopaedic, Scripps Green Hospital

    La Jolla, California, 92037, United States

  • Spine Team Texas, Texas Health Harris Methodist Hospital Southlake

    Southlake, Texas, 76092, United States

  • Stanford University

    Redwood City, California, 94063, United States

  • Swedish Medical Center

    Seattle, Washington, 98122, United States

  • The Center for Advanced Orthopaedics, Adena Bone and Joint Center

    Chillicothe, Ohio, 45601, United States

  • The Spine Institute, St. John's Health Center

    Santa Monica, California, 90404, United States

  • UCSD Department of Orthpaedic Surgery, UCSD Medical Center

    San Diego, California, 92103, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19106, United States

  • University of South Florida Department of Neurosurgery, Tampa General Hospital

    Tampa, Florida, 33606, United States

  • Winchester Medical Center

    Winchester, Virginia, 22601, United States