Could adding chemo to standard pill beat lung cancer better?
NCT ID NCT04410796
First seen Nov 01, 2025 · Last updated May 01, 2026 · Updated 31 times
Summary
This study looks at people with a specific type of advanced lung cancer (EGFR-mutant) that has spread. It compares the usual treatment, a pill called osimertinib, against osimertinib plus chemotherapy. The goal is to see if the combination can keep the cancer from growing longer. About 571 adults with detectable cancer DNA in their blood after starting osimertinib will take part.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Columbia University (Data Collection Only)
ACTIVE_NOT_RECRUITINGNew York, New York, 10032, United States
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Hackensack Meridian Health
RECRUITINGHackensack, New Jersey, 07601, United States
Contact Phone: •••-•••-••••
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John Hopkins Medical Center
RECRUITINGBaltimore, Maryland, 21287, United States
Contact Phone: •••-•••-••••
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MD ANDERSON CANCER CENTER (Data Collection Only)
RECRUITINGHouston, Texas, 77030, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Massachusetts General Hospital (Data Collection Only)
RECRUITINGBoston, Massachusetts, 02114, United States
Contact Phone: •••-•••-••••
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Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)
RECRUITINGBasking Ridge, New Jersey, 07920, United States
Contact Phone: •••-•••-••••
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Memorial Sloan Kettering Bergen (Limited Protocol Activities)
RECRUITINGMontvale, New Jersey, 07645, United States
Contact Phone: •••-•••-••••
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Memorial Sloan Kettering Cancer Center (All protocol activities)
RECRUITINGNew York, New York, 10065, United States
Contact Phone: •••-•••-••••
Contact Phone: •••-•••-••••
Contact
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Memorial Sloan Kettering Commack (Limited protocol activities)
RECRUITINGCommack, New York, 11725, United States
Contact Phone: •••-•••-••••
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Memorial Sloan Kettering Monmouth (Limited Protocol Activities)
RECRUITINGMiddletown, New Jersey, 07748, United States
Contact Phone: •••-•••-••••
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Memorial Sloan Kettering Nassau (Limited Protocol Activities)
RECRUITINGUniondale, New York, 11553, United States
Contact Phone: •••-•••-••••
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Memorial Sloan Kettering Westchester (Limited protocol activities)
RECRUITINGHarrison, New York, 10604, United States
Contact Phone: •••-•••-••••
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Moffitt Cancer Center
RECRUITINGTampa, Florida, 33612, United States
Contact Phone: •••-•••-••••
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New York University
RECRUITINGNew York, New York, 10010, United States
Contact Phone: •••-•••-••••
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Sarah Cannon Research Institute
RECRUITINGNashville, Tennessee, 37203, United States
Contact Phone: •••-•••-••••
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UC Davis Cancer Center (Data Collection Only)
RECRUITINGSacramento, California, 95817, United States
Contact Phone: •••-•••-••••
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University of California San Francisco
ACTIVE_NOT_RECRUITINGSan Francisco, California, 94143, United States
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University of Washington (Data Collection Only)
RECRUITINGSeattle, Washington, 98109, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
Explore the condition pages connected to this study.