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New combo targets stubborn lung cancer cells that survive initial therapy

NCT ID NCT07375316

First seen Jan 30, 2026 · Last updated Jun 02, 2026 · Updated 9 times

Summary

This study is for people with advanced EGFR-mutated non-small cell lung cancer whose cancer still shows signs of activity (detected by a blood test) after taking the drug osimertinib alone. The trial will test whether adding a second drug, sacituzumab tirumotecan, can improve outcomes. About 120 participants will receive the combination and be monitored for cancer progression and side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-••••

Locations

  • Guangdong Lung Cancer Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University

    RECRUITING

    Guangzhou, Guangdong, 510080, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Meizhou People's Hospital (Huangtang Hospital), Meizhou Academy of Medical Sciences

    RECRUITING

    Meizhou, Guangdong, 514031, China

    Contact

  • Peking University Shenzhen Hospital

    RECRUITING

    Shenzhen, Guangdong, 518036, China

    Contact

  • The First Affiliated Hospital of Shantou University Medical College

    RECRUITING

    Shantou, Guangdong, 515041, China

Conditions

The condition(s) this trial relates to.

non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.