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Infant immune booster shows promise against wheezing

NCT ID NCT02148796

First seen Feb 23, 2026 · Last updated May 23, 2026 · Updated 9 times

Summary

This study tested whether a daily oral bacterial extract, Broncho-Vaxom, could prevent wheezing lower respiratory tract infections in infants at high risk for asthma. Over 800 infants aged 6-18 months received either the extract or a placebo for 10 days each month over two years. The main goal was to see if the treatment delayed the first wheezing episode during a three-year follow-up period.

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Contacts and locations

Locations

  • Boston Children's Hospital, Harvard University

    Boston, Massachusetts, 02115, United States

  • Children's National Health System

    Washington D.C., District of Columbia, 20037, United States

  • Cincinnati Children's Hospital & Medical Center

    Cincinnati, Ohio, 45229, United States

  • Columbia University

    New York, New York, 10032, United States

  • Emory University

    Atlanta, Georgia, 30322, United States

  • Phoenix Children's Hospital

    Phoenix, Arizona, 85016, United States

  • University of Arizona

    Tucson, Arizona, 85724, United States

  • University of California San Francisco, Benioff Children's Hospital

    Oakland, California, 94609, United States

  • University of North Carolina

    Chapel Hill, North Carolina, 27514, United States

  • University of Wisconsin

    Madison, Wisconsin, 53792-4108, United States

  • Washington University

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.