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Daily pill shows promise for diabetes control in real life

NCT ID NCT05443568

First seen Nov 01, 2025 · Last updated Jun 20, 2026 · Updated 43 times

Summary

This study looked at how well once-daily oral semaglutide (Rybelsus) works for adults with type 2 diabetes in everyday medical practice in Israel. Researchers tracked changes in blood sugar and body weight over about 8-10 months. The goal was to see if the pill helps lower blood sugar levels in a real-world setting.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Master Centre for Israel

    Kfar Saba, 44425, Israel

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

semaglutide (Rybelsus)

What this could lead to

If successful, this study could confirm that oral semaglutide helps manage blood sugar and weight in real-world settings, supporting its use for type 2 diabetes.

What could go wrong

This is an observational study with no control group, so results may not prove cause and effect. It is also completed and not testing a new treatment, so no breakthrough is expected.

Conditions

The condition(s) this trial relates to.

type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.