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Real-World study tests daily pill for diabetes control

NCT ID NCT05316662

First seen Nov 01, 2025 · Last updated Jun 19, 2026 · Updated 30 times

Summary

This completed study in Mexico followed 187 adults with type 2 diabetes who were already prescribed oral semaglutide (Rybelsus) by their doctor. The goal was to see how well the once-daily pill lowers blood sugar and affects body weight over 8-10 months. Participants also filled out questionnaires about their treatment. The study is observational, meaning it simply collected data from routine care without changing how patients were treated.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • CICEJ Centro de Investigacion Clinica Endocrinologica de Jalisco SC

    Guadalajara, Jalisco, 44670, Mexico

  • Centro de Investigacion Clinica Endocrinologica de Jalisco

    Guadalajara, Jalisco, 44670, Mexico

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

semaglutide (Rybelsus)

What this could lead to

If results are positive, this could confirm that oral semaglutide helps control blood sugar and weight in real-world settings, supporting its use for type 2 diabetes.

What could go wrong

This is an observational study without a comparison group, so results may be influenced by other factors. It also only includes Mexican adults, so findings may not apply to everyone.

Conditions

The condition(s) this trial relates to.

type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.