Pill vs. gel: which works better for starting labor?
NCT ID NCT04955847
First seen Jun 12, 2026 · Last updated Jun 23, 2026 · Updated 3 times
Summary
This study compared two drugs used to start labor in pregnant women at full term with an unfavorable cervix. One group received oral misoprostol pills, the other received vaginal dinoprostone gel or insert. Researchers tracked how many women delivered vaginally within 24 hours, as well as rates of C-sections and side effects. The trial included 706 women and has already been completed.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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CHU Amiens Picardie
Amiens, France
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
misoprostol (oral) and dinoprostone (vaginal)
What this could lead to
If oral misoprostol proves as safe and effective as vaginal dinoprostone, it could offer a simpler, cheaper option for inducing labor.
What could go wrong
This is a single-center study comparing two time periods, not a randomized trial, so results may be influenced by other changes in care. The findings may not apply to all hospitals or patients.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.