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Kitchen remedies tested against Hospital-Grade mouthwash in ICU

NCT ID NCT07365956

Disease control Sponsor: Harran University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested three mouth care methods—apple cider vinegar, chlorhexidine (a common antiseptic), and baking soda—in 90 intensive care patients after brain surgery. The goal was to see which best reduces harmful mouth bacteria that can lead to pneumonia. All treatments were given as part of routine oral hygiene over five days.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Chlorhexidine gluconate, sodium bicarbonate, and apple cider vinegar
What this could lead to
If effective, these simple oral care methods could help prevent serious lung infections in ICU patients.
What could go wrong
This is a small, completed study with no phase, so results may not apply broadly. The interventions are common and low-risk, but the benefit over standard care is uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

90 people

The number who actually took part.

Started

Jan 2021

Finished

Jan 2022

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Mechanical ventilation was initiated less than 24 hours ago, * Aged 18 years or older, * Had not undergone any oral surgical procedure, * Were not leukopenic or thrombocytopenic, * And had no oral infection such as aphthous ulcer, stomatitis, or gingivitis. Exclusion Criteria: * Mechanical ventilation was initiated more than 24 hours ago, * Under 18 years of age, * Had undergone any oral surgical procedure, * Were leukopenic or thrombocytopenic, * Or had an oral infection such as aphthous ulcer, stomatitis, or gingivitis.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Oral care

Contacts and locations

Locations

  • Inonu University

    Malatya, 44050, Turkey (Türkiye)

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