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New MRI sequences aim to sharpen images and ease patient discomfort

NCT ID NCT05326581

Knowledge-focused Sponsor: Fondation Ophtalmologique Adolphe de Rothschild Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study aims to improve MRI scans by testing different sequence settings to get clearer images and make the exam more comfortable. Researchers will compare the standard MRI sequence with several new variants in 750 adults, including patients and healthy volunteers. The goal is to find the best balance of image quality, diagnostic confidence, and patient experience.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
MRI (magnetic resonance imaging) device
What this could lead to
If successful, this could lead to faster, more comfortable MRI scans with clearer images, improving diagnosis for many patients.
What could go wrong
This is an early optimization study, not a treatment trial. The new sequences may not significantly improve quality or comfort, and results may not apply to all MRI machines or conditions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 750 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2022

Expected to finish

May 2027

An estimate. End dates often move.

Lead sponsor

A research network

The lead sponsor is a research network or cooperative group.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Participation in the study will be offered to patients performing MRI imaging as part of the treatment as well as to healthy volunteers among the staff.

Ages

18 months and older

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Subject over 18 years old * Consent to participate in the study * Member of or beneficiary of a social security scheme * For patients: benefiting from an MRI examination as part of their care * For volunteers: Consent to be informed if an unexpected anomaly is revealed by the imaging. Exclusion Criteria: * Subject benefiting from a measure of legal protection * Pregnant or breastfeeding women * For volunteers: Contraindication to MRI (detailed contraindications questionnaire, THI score \>28 questionnaire, hearing sensitivity questionnaire grade \>1)

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Optimized mri sequences

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Hôpital Fondation Adolphe de Rothschild

    RECRUITING

    Paris, Paris, 75019, France