Can simple samples predict transplant success? new study aims to unlock clues for Longer-Lasting organs

NCT ID NCT03997253

Knowledge-focused Sponsor: University Hospital, Limoges Source: ClinicalTrials.gov ↗

First seen Jun 29, 2026 · Last updated Jun 30, 2026 · Updated 1 time

Summary

This study follows 430 adults who have received a kidney, liver, or heart transplant to understand what factors help transplanted organs survive longer. Researchers collect blood, urine, and bile samples at several time points over the first year after transplant. The goal is to find early signs of rejection and improve long-term care for transplant recipients.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to: If successful, this research could identify markers to predict transplant rejection and extend the life of transplanted organs, improving long-term outcomes for recipients.
What could go wrong: This is an observational study, not a treatment trial. It may not directly lead to new therapies, and findings may take years to translate into clinical practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 430 people

The number the study aims to enrol. It can still change while the study runs.

Started

Dec 2020

Expected to finish

Jun 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male or female over 18 (no age limit) * affiliated to a social security organization * Recipient (s) of a kidney, liver or heart transplant * followed by at least one of the FHU SUPORT centers (Tours, Poitiers, Limoges, Rennes) * having given informed consent to participate in the cohort. Exclusion Criteria: * Patient unable to understand the information given by the investigator * People under the protection of justice

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Organ transplantation

How to take part

Only the study team decides who joins. These are the ways to reach them.

The places running it

4 sites. The list below names each one and where it is.
The official record

ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

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A doctor treating you

A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Can simple samples predict transplant success? new study aims to unlock clues for Longer-Lasting organs

What the study statuses mean