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New community program aims to curb antibiotic resistance in africa

NCT ID NCT05378880

Knowledge-focused Sponsor: Institute of Tropical Medicine, Belgium Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a community program in Burkina Faso and DR Congo to improve how antibiotics are used and to reduce the spread of resistant bacteria. Over 5,500 people participated, including medicine store staff and community members. The program involved education and behavior change to promote better antibiotic use and hygiene. Results will show if this approach can lower antibiotic resistance in these communities.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
behavioural intervention bundle
What this could lead to
If successful, this approach could help reduce antibiotic resistance in low-income communities by promoting better antibiotic use and hygiene.
What could go wrong
This is a completed study, but results may not apply to other regions. The intervention's impact depends on local cooperation and may not lead to lasting change.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

5,532 people

The number who actually took part.

Started

May 2022

Finished

Dec 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Patient exit surveys Inclusion Criteria: * Visitor to a medicine dispenser for his/her own health or that of someone else, regardless of disease or age * Having just completed a visit to a medicine dispenser in a study cluster who agreed to participate in the study Exclusion Criteria: none Simulated patient visits (dispensers) Inclusion criteria: * Prescribe or dispense medicines in a community pharmacy, medicine store, or other private clinic or outlet within the selected study clusters; * Consented at the start of the study to participate in the intervention bundle evaluation Exclusion Criteria: none Faecal Enterobacteriaceae carriage and transmission (members of selected households) and household surveys (household heads) Inclusion criteria * Member of a household in a study cluster (resident for \>/= 3 months); * Agreement of the household head for all household members (including children) to participate to the collection of four stool samples during the study period, through informed written consent; * Individual informed consent (plus assent for adolescent participants) for each participating household member; * be in good physical health (no current infectious disease); Exclusion criteria * Inhabitant of study clusters who planned to move or be absent during the following year; * Temporary exclusion: Ongoing infectious disease or ongoing treatment for an infectious disease. Field workers will return to collect stools once the patient has recovered

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Antimicrobial stewardship Drug resistance, bacterial

Contacts and locations

Locations

  • Centre de Recherche en Santé de Kimpese (CRSK)

    Kimpese, Democratic Republic of the Congo

  • Clinical Research Unit of Nanoro (CRUN)

    Nanoro, Burkina Faso

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