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New creatine formula tested for better absorption and less stomach trouble

NCT ID NCT07225335

First seen Nov 06, 2025 · Last updated Jun 22, 2026 · Updated 31 times

Summary

This study tested a new creatine supplement called OptiCreatine against standard creatine monohydrate in 17 healthy, active adults. The goal was to see if OptiCreatine leads to higher creatine levels in the blood and fewer stomach issues. Participants took both supplements at different times, and researchers measured absorption and digestive comfort.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Applied Physiology Laboratory (Fetzer Hall, Room 025)

    Chapel Hill, North Carolina, 27599-8700, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

OptiCreatine (a dietary supplement combining creatine with other compounds)

What this could lead to

If OptiCreatine works better, it could mean less stomach discomfort and better absorption for people who take creatine supplements.

What could go wrong

This was a very small study (17 people) in healthy adults, so results may not apply to everyone. The supplement industry often makes bold claims that don't hold up in larger trials.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.