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Can opioids help cancer patients breathe easier during exercise?

NCT ID NCT04188418

First seen Feb 26, 2026 · Last updated Apr 30, 2026 · Updated 7 times

Summary

This study tests whether fast-acting opioids (fentanyl or morphine) can reduce shortness of breath during physical activity in 150 cancer patients who already take strong painkillers. Participants will take the drug or a placebo before a walking test, and their breathing difficulty will be measured. The goal is to find a new way to improve daily comfort and activity for people with advanced cancer.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

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