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Which anesthesia works best for bariatric surgery? new study aims to find out

NCT ID NCT06390046

Knowledge-focused Sponsor: Jagiellonian University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed trial compared two types of opioid-free anesthesia—total intravenous (TIVA) versus inhaled gas—in 280 adults undergoing laparoscopic bariatric surgery. The main goal was to see which method reduces postoperative nausea and vomiting in the first 24 hours. Researchers also tracked pain levels and how quickly patients recovered. Both techniques are already used in practice, but this study aims to provide clearer guidance for anesthesiologists.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
opioid-free anesthesia (TIVA vs inhalational agent)
What this could lead to
If one method proves better, it could guide anesthesiologists to reduce nausea and speed recovery after weight-loss surgery.
What could go wrong
This is a completed study comparing two already-approved techniques, so no major breakthrough is expected. Results may not apply to all surgery types.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

280 people

The number who actually took part.

Started

Apr 2024

Finished

Dec 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients over 18 years who underwent laparoscopic bariatric surgery Exclusion Criteria: Patients with a history of allergic reactions to drugs Patients with a history of drug addiction Patients with chronic pain who require analgesics History of hospitalization for psychiatric disorders Preoperative pulse oximetry (SpO2) \< 95 % bradycardia (HR\<50bpm), hypotension, atrioventricular block, intraventricular or sinus block Blood clotting disorders Pregnant/lactating women Cognitive impairment Unable to read consent

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Conditions

The condition(s) this trial relates to.

obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Analgesics, opioid Anesthesia; adverse effect

Contacts and locations

Locations

  • Jagiellonian University

    Krakow, Lesser Poland Voivodeship, 31501, Poland

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