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Liquid bandage for internal bleeding? new study tests onyx™

NCT ID NCT06742801

First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 41 times

Summary

This study tests a liquid called Onyx™ that hardens to block bleeding arteries. It is for people with active bleeding from trauma, ulcers, or other causes outside the heart and brain. Researchers will check if it safely stops the bleed without needing more procedures within 30 days. About 119 adults will take part.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Albany Medical Center

    RECRUITING

    Albany, New York, 12208, United States

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

  • CHI Health Creighton University Medical Center-Bergan-Mercy

    RECRUITING

    Omaha, Nebraska, 68124, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Masschusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02114, United States

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

  • Mayo Clinic

    RECRUITING

    Phoenix, Arizona, 85054, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

  • Rutgers New Jersey Medical School

    RECRUITING

    Newark, New Jersey, 07103, United States

    Contact

    Contact Email: •••••@•••••

  • Stanford Medical Center

    RECRUITING

    Palo Alto, California, 94304, United States

    Contact

    Contact

  • The Mount Sinai

    RECRUITING

    New York, New York, 10029, United States

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

  • The Ohio State University

    RECRUITING

    Columbus, Ohio, 43210, United States

    Contact

    Contact Email: •••••@•••••

  • The University of Texas Health Science Center at Houston

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

    Contact

  • UCHealth University of Colorado Hospital

    RECRUITING

    Aurora, Colorado, 80045, United States

    Contact Email: •••••@•••••

    Contact

  • Univ Of Texas Southwestern

    RECRUITING

    Dallas, Texas, 75235, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University Hospitals Cleveland Medical Center

    RECRUITING

    Cleveland, Ohio, 44106, United States

    Contact Email: •••••@•••••

    Contact

  • University of California, Irvine

    RECRUITING

    Irvine, California, 92627, United States

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

  • University of Chicago

    RECRUITING

    Chicago, Illinois, 60637, United States

    Contact

    Contact Email: •••••@•••••

  • University of Iowa Hospitals and Clinics

    RECRUITING

    Iowa City, Iowa, 52242, United States

    Contact

    Contact

  • University of Pittsburgh Medical Center

    RECRUITING

    Pittsburgh, Pennsylvania, 15237, United States

    Contact

    Contact Email: •••••@•••••

  • Vanderbilt University Medical Center

    RECRUITING

    Nashville, Tennessee, 37212, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Yale New Haven

    RECRUITING

    New Haven, Connecticut, 06510, United States

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Onyx™ Liquid Embolic System (a liquid that hardens to block bleeding arteries)

What this could lead to

If successful, this could provide a quick, minimally invasive way to stop severe bleeding in trauma or ulcers without surgery.

What could go wrong

This is an early-stage study with only 119 people, so results may not apply to everyone. Risks include the liquid moving to the wrong spot or not stopping the bleed.

Conditions

The condition(s) this trial relates to.

Gastrointestinal Hemorrhage Hemorrhage injury ulcer disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.