Family chat program boosts medication adherence in schizophrenia
NCT ID NCT07545941
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested an online family education program delivered via a messaging app to help families of people with first-episode schizophrenia. The goal was to reduce negative emotions in family members and improve how consistently patients take their medication. 53 patients and their families participated, with the program focusing on communication and support strategies.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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53 people
The number who actually took part.
- Started
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May 2025
- Finished
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Sep 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion criteria for patients were: * a diagnosis of schizophrenia according to the International Classification of Diseases, 10th Revision ICD-10 (F20.00 to F20.09), with a duration of illness not exceeding five years from the date of initial diagnosis * received oral antipsychotic treatment for at least 6 months but no longer than five years * aged between 18 to 35 years. * mild psychotic symptoms severity, defined as a total score of 18 to 36 on the Brief Psychiatric Rating Scale (BPRS) * documented history of medication non-adherence, as recorded in medical records * availability of a primary caregiver and * ability to communicate in Thai and via telephone using the LINE application Inclusion criteria for family members were: * being a family member living in the same household as the patients and serving as the primary caregiver for at least six months without financial compensation * Aged 20 to 60 years * ownership of a mobile phone capable of using the LINE application * no prior participation in family psychoeducation programs * ability to speak, read, and write Thai * no history of psychiatric disorders, including schizophrenia, bipolar disorder, or major depressive disorder. Exclusion criteria for both patients and caregivers were: * acute exacerbation of psychotic symptoms requiring hospitalization during the study period * missing one or more scheduled intervention sessions * inability of the researcher to contact the family caregiver within one week despite repeated attempts.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Faculty of Nursing, Mahidol University
Bangkok Noi, Bangkok, 10700, Thailand