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AI-Powered online therapy aims to ease depression and anxiety

NCT ID NCT06350201

Symptom relief Sponsor: Wuhan Mental Health Centre Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Sep 09, 2026 · Updated 7 times

Summary

This study tests whether an online problem-solving therapy, matched to a person's specific symptoms using machine learning, can reduce depression and anxiety better than usual care. About 380 adults with moderate symptoms will take part. The goal is to create a precise, scalable treatment that can be delivered online.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
online problem-solving therapy
What this could lead to
If it works, this could provide a personalized, scalable online treatment to reduce depression and anxiety symptoms.
What could go wrong
This is an early-stage study without a drug; results may not generalize beyond the specific online intervention or population.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

409 people

The number who actually took part.

Started

Sep 2025

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 64 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Aged between 18 and 64 years. PHQ-9 ≥10 and/or GAD-7 ≥8 at baseline assessment defined as the threshold for caseness. Exclusion Criteria: * People will be excluded if they meet any of the following criteria: 1. They are receiving psychological therapy during an interview for any mental health issue; 2. currently acutely suicidal or have attempted suicide in the past 2 months, as indicated by PHQ-9 item 9; 3. cognitively impaired or diagnosed with bipolar disorder or psychosis or experiencing psychotic symptoms; d) dependent on alcohol or drugs; e) living with an unstable or acute medical illness that would interfere with trial participation.

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Conditions

The condition(s) this trial relates to.

anxiety anxiety disorder Depression depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Depression and anxiety symptom

Contacts and locations

Locations

  • Renmin Hospital of Wuhan University

    Wuhan, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.