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New dental protocol could save worn teeth without drilling

NCT ID NCT07533240

Knowledge-focused Sponsor: Mainjot Amélie Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at a new way to fix worn-down teeth using a minimally invasive approach called the One-Step No-Prep protocol. It combines small tooth-colored restorations with simple braces-like movements to improve bite and jaw function. Researchers will track 30 adults to see how teeth move, how the jaw joint adapts, and how stable the results are over time.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
One-Step No-Prep protocol (minimally invasive bonded restorations with orthodontic mechanics)
What this could lead to
If successful, this could provide a less invasive, more predictable way to restore worn teeth and improve bite function.
What could go wrong
This is a small, early-stage study with only 30 participants, so results may not apply to everyone. The treatment's long-term stability and safety are still being evaluated.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 30 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Apr 2026

An estimate. Start dates often move.

Expected to finish

Feb 2041

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Localized tooth wear that will be treated, or has already been treated, using the OSNPO protocol. * Age 18 years or older. * Sufficient cognitive ability to understand the study procedures and complete the required assessments. * Ability to read and complete the study questionnaires in French. * Written informed consent provided. Exclusion Criteria: * No exclusion criteria.

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Conditions

The condition(s) this trial relates to.

tooth erosion, non-bacterial Tooth Wear

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Orthodontic extrusion Tooth wear

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • University Hospital of Liège

    RECRUITING

    Liège, 4000, Belgium

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