Fish oil pills could help fight prostate cancer, new study hints
NCT ID NCT02333435
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This phase 2 trial tests whether taking omega-3 (EPA) supplements can reduce inflammation and slow cancer cell growth in men with high-risk prostate cancer who choose surgery. 130 participants will take either EPA capsules or a placebo for 14 months, starting before surgery. Researchers will measure changes in tumor growth markers and quality of life.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Omega-3 (EPA) dietary supplement
- What this could lead to
- If it works, this could point toward a simple dietary supplement to help control prostate cancer growth and improve quality of life after surgery.
- What could go wrong
- This is an early phase 2 trial with only 130 participants. The supplement may not show a clear benefit, and results may not apply to all prostate cancer patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Phase 2
Tests whether the treatment actually works, and watches for side effects, in a larger group.
- Participants
-
130 people
The number who actually took part.
- Started
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Feb 2015
- Expected to finish
-
Dec 2025
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Male participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Prostate cancer (Gleason score \>= 7) * Patient has chosen to undergo radical prostatectomy * Patient agrees to stop taking any omega-3 supplements at least 3 months before the start of the study * Patient has provided informed consent Exclusion Criteria: * Allergy to fish and sunflower * Suffering from a bipolar disorder
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Centre de Recherche Clinique et Evaluative en Oncologie - Hotel Dieu de Quebec
Québec, Quebec, G1R 3S1, Canada
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- A scanner in the operating room could show surgeons exactly where prostate cancer remains
- New PET tracer aims to light up hidden cancer targets
- Can daily adaptive radiotherapy spare healthy tissue in prostate cancer?
- Can a radioactive tracer and MRI reveal prostate Cancer's true extent?
- Five-Fraction radiation plus hormone therapy tested against High-Risk prostate cancer
- Can a 10-Hour eating window fight cancer fatigue?