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Fish oil pills tested for lowering fat levels in overweight chileans

NCT ID NCT06538324

Disease control Sponsor: Universidad San Sebastián Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether low-dose omega-3 supplements (250 mg EPA per day) can improve cholesterol and inflammation in overweight or obese adults with high triglycerides. Forty participants in Chile took omega-3 or a placebo for six weeks each in a crossover design. The goal was to see if this simple dietary change could help control blood fat levels.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Omega-3 fatty acids (EPA) and high-oleic sunflower oil (HOSO) as a placebo
What this could lead to
If it works, this could point toward a simple dietary supplement to help manage high triglycerides in overweight individuals.
What could go wrong
This is a small, completed trial with only 40 participants, so results may not apply broadly. The omega-3 dose is low (250 mg EPA per day), which may not be enough to produce meaningful changes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

40 people

The number who actually took part.

Started

Jul 2024

Finished

Jun 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults between 18 and 65 years old, male and female. * Body mass index (BMI) between 25 - 34,9 kg/m2. * Fasting triglycerides between 100-215 mg/dL (1.13-2.43 mmol/L). Exclusion Criteria: * Unable to give informed consent. * If you consume Omega-3 (you must stop consumption at least 10 weeks prior). * Normal or Obesity Nutritional Status. Large weight variation (\>10%) in the last 3 months. * Triglycerides \> 215 mg/dL. * Blood pressure \> 140/90 mmHg. * Uncontrolled metabolic and chronic diseases (reference parameters for the disease in question will be considered). * Pregnant women or those who are breastfeeding. * Allergy or intolerance to gluten, milk protein and/or lactose, or any ingredient in the capsules (omega-3, oleic acid oil). * Use of medications that affect lipid metabolism: Fibrates. (Statins will be allowed only if the treatment has been ongoing for over 3 months). * Blood donation two months before or during the study period. * Excessive alcohol consumption (\>3 cans of beer per day) * Taking anticoagulants.

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Conditions

The condition(s) this trial relates to.

hypertriglyceridemia Overweight

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hypertriglyceridemia Overweight

Contacts and locations

Locations

  • Universidad San Sebastián

    Valdivia, Los Ríos Region, 5090000, Chile

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