New anesthesia drug tested for safer surgery in endometrial cancer patients
NCT ID NCT07372209
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether oliceridine, a newer painkiller, is as safe and effective as the standard drug sufentanil for putting patients to sleep before gynecologic laparoscopic surgery. 120 women with endometrial cancer took part. Researchers monitored blood pressure and heart rate changes during anesthesia induction and tracked any side effects.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Oliceridine and sufentanil (analgesic drugs used for anesthesia)
- What this could lead to
- If oliceridine proves safer or more stable than sufentanil, it could offer a better option for anesthesia induction in gynecologic surgeries.
- What could go wrong
- This is a small, completed study with 120 participants, so results may not apply broadly. The drugs are already approved, so no major breakthrough is expected.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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120 people
The number who actually took part.
- Started
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Oct 2025
- Finished
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Dec 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Age 18-65 years; 2. American Society of Anesthesiologists (ASA) physical status I-II; 3. Elective gynecologic laparoscopic surgery; 4. Expected operative time 60-180 minutes; Exclusion Criteria: 1. Severe cardiovascular instability (e.g., acute decompensated heart failure, acute myocardial infarction, or life-threatening arrhythmia); 2. Uncontrolled hypertension; 3. Severe renal or hepatic dysfunction; 4. Severe mental disorder or psychiatric illness; 5. Known allergy or hypersensitivity to opioids; 6. History of alcohol abuse or opioid addiction; 7. Anticipated difficult airway; 8. Pregnancy or lactation;
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Tangshan Maternal and Child Health Hospital
Tangshan, Hebei, 063000, China
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