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New hope for rare autoimmune disease: ofatumumab tested in NMOSD pilot

NCT ID NCT05504694

First seen Feb 01, 2026 · Last updated Jun 17, 2026 · Updated 19 times

Summary

This pilot study tests the drug ofatumumab in 5 adults with a rare autoimmune disease called NMOSD that attacks the nerves in the eyes and spine. The goal is to see if the drug can reduce the number of relapses and slow disability. Participants must have had at least 2 relapses in the past 2 years and test positive for AQP4 antibodies.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Tangdu Hospital

    RECRUITING

    Xi'an, Shaanxi, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

neuromyelitis optica

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.