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New study tracks how kidney cancer patients fare in everyday clinics

NCT ID NCT04919122

Knowledge-focused Sponsor: Duke University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Aug 06, 2026 · Updated 3 times

Summary

This study follows 468 people with metastatic kidney cancer to see how their treatment and quality of life change over time in real-world clinics. Researchers will track medication adherence, symptoms, and well-being using patient questionnaires. The goal is to understand what actually happens outside of controlled trials, not to test a new drug.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

468 people

The number who actually took part.

Started

Apr 2022

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients with metastatic renal cell cancer (mRCC) will be identified and undergo consent and baseline assessments, including research blood collection and processing. Patient reported outcomes will be collected at baseline (pre-treatment) every 3 months for 2 years, and then every 6 months until end of follow up (with a minimum follow-up of 18 months and a maximum follow-up period of 36 months; additional follow up will be obtained based on continuous funding).

Ages

19 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 19 or over at time of informed consent. * Diagnosis of metastatic renal cell cancer (mRCC) with less than or equal to (≤) 3 months of first-line systemic therapy or less than or equal to (≤) 3 months of second-line systemic therapy for mRCC. 1. Prior surgery and radiation therapy are permitted. 2. Prior neoadjuvant and adjuvant therapy for non-metastatic renal cell carcinoma are permitted. 3. Patients currently not on therapy and being observed are permitted. * Evidence of signed and dated informed consent document indicating that the patient has been informed of all pertinent aspects of the study. * Ability to comply with completion of PROs Exclusion Criteria: * Patients being treated for metastatic solid tumors other than mRCC are excluded. Non-cytotoxic oral agents for adjuvant or maintenance therapy of other cancers are permitted. * Patients who are not intending to undergo follow up care at a study site within PCORnet

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Conditions

The condition(s) this trial relates to.

renal cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Metastatic renal cell carcinoma

Contacts and locations

Locations

  • Duke University

    Durham, North Carolina, 27710, United States

  • Geisinger Clinic

    Danville, Pennsylvania, 17822, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • Ochsner Clinic Foundation d/b/a Ochsner Health

    New Orleans, Louisiana, 70121, United States

  • State University of Iowa

    Iowa City, Iowa, 52242, United States

  • The Johns Hopkins University

    Baltimore, Maryland, 21205, United States

  • The Medical College of Wisconsin, Inc.

    Milwaukee, Wisconsin, 53226, United States

  • The Ohio State University

    Columbus, Ohio, 43210, United States

  • The Regents of the University of Michigan

    Ann Arbor, Michigan, 48109, United States

  • The University of North Carolina at Chapel Hill

    Chapel Hill, North Carolina, 27599, United States

  • The University of Texas Southwestern Medical Center

    Dallas, Texas, 75390, United States

  • University of Kansas Medical Center

    Kansas City, Kansas, 66160, United States

  • University of Pittsburgh

    Pittsburgh, Pennsylvania, 15260, United States

  • University of Utah

    Salt Lake City, Utah, 84112, United States

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