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New hope for rare liver disease: drug may delay surgery in kids

NCT ID NCT06850038

First seen Nov 01, 2025 · Last updated May 24, 2026 · Updated 28 times

Summary

This study follows 30 people with Alagille syndrome, a rare liver disease that causes severe itching and growth problems, as they take the drug odevixibat in real life. Researchers want to see if the medicine helps patients avoid major surgeries like bile duct rerouting or liver transplant, and whether it improves weight and height over time. The goal is to understand how well odevixibat works and how safe it is when used outside of a strict clinical trial setting.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Childrens Hospital Los Angeles

    RECRUITING

    Los Angeles, California, 90027, United States

  • Columbia University

    RECRUITING

    New York, New York, 10016, United States

  • Le Bonheur Children's Hospital

    RECRUITING

    Memphis, Tennessee, 38105, United States

  • NYU Langone - NYU Grossman School of Medicine

    RECRUITING

    New York, New York, 10016, United States

  • Proactive El Paso,LLC

    RECRUITING

    El Paso, Texas, 79902, United States

  • St Louis University. SSM Cardinal Glennon Childrens Medical Center

    RECRUITING

    St Louis, Missouri, 63104, United States

  • The Children's Mercy Hospital

    RECRUITING

    Kansas City, Missouri, 64108, United States

  • UCSF Pediatric Gastroenterology

    RECRUITING

    San Francisco, California, 94158, United States

  • UT Southwestern Childrens Medical Center

    RECRUITING

    Dallas, Texas, 75235, United States

Conditions

Explore the condition pages connected to this study.