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New study aims to sharpen diagnosis of dangerous heart blockages

NCT ID NCT06272643

Diagnosis Sponsor: Fundación EPIC Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two imaging techniques, OCT and IVUS, used to evaluate blockages in a key heart artery. Researchers want to see if OCT can better identify which blockages need treatment. The study involves 153 adults with moderate blockages and will track their heart health over time.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

153 people

The number who actually took part.

Started

Apr 2024

Expected to finish

Apr 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients with intermediate lesion in the LMCA (Left Main Coronary Artery) (25-60% angiographic stenosis by visual estimation) in whom a study with intracoronary imaging technique is considered (at least one pullback with IVUS (Intravascular ultrasound) and OCT (OPTICAL COHERENCE TOMOGRAPHY) from one of the main branches is mandatory)

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients aged ≥18 years * Patients with intermediate lesion in the LMCA (Left Main Coronary Artery) (25-60% angiographic stenosis by visual estimation) in whom a study with intracoronary imaging technique is considered (at least one pullback with IVUS (Intravascular ultrasound) and OCT (OPTICAL COHERENCE TOMOGRAPHY) from one of the main branches is mandatory). * Patients able to give informed consent form. Exclusion Criteria: * Patients with indication for coronary surgery regardless of significance of LMCA lesion. * Patients with LMCA lesion showing ulceration, dissection or thrombus. * Patients with lesion in a previous functioning arterial or venous graft in the territory supplied by the LMCA (protected LMCA). * Patients with acute coronary syndrome with potentially culpable injury in LMCA. * Patients unable to give informed consent. * Patients with ostial LMCA lesion.

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Conditions

The condition(s) this trial relates to.

coronary artery disorder Coronary Disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Coronary disease

Contacts and locations

Locations

  • Hospital Clinico San Carlos

    Aravaca, 28040, Spain

  • Hospital Clinico Universitario de Valladolid

    Valladolid, 47003, Spain

  • Hospital Clínico Universitario Virgen de la Arrixaca

    El Palmar, 30120, Spain

  • Hospital Clínico Universitario de Salamanca

    Salamanca, 37007, Spain

  • Hospital General Universitari Dr Balmis

    Alicante, 03010, Spain

  • Hospital Universitari Vall Hebron

    Barcelona, 08035, Spain

  • Hospital Universitari de Bellvitge

    L'Hospitalet de Llobregat, 08907, Spain

  • Hospital Universitario Juan Ramon Jimenez

    Huelva, 21005, Spain

  • Hospital Universitario La Paz

    Madrid, 28046, Spain

  • Hospital Universitario Lozano Blesa

    Zaragoza, 50009, Spain

  • Hospital Universitario Marques de Valdecilla

    Santander, 39008, Spain

  • Hospital Universitario Puerta del Mar

    Cadiz, 11009, Spain

  • Hospital Universitario Reina Sofía

    Córdoba, 14004, Spain

  • Hospital Universitario Virgen Del Rocio

    Seville, 41013, Spain

  • Hospital Universitario de Cabueñes

    Gijón, 33394, Spain

  • Hospital Universitario de Jerez de La Frontera

    Jerez de la Frontera, 11407, Spain

  • Hospital Universitario de La Princesa

    Madrid, 28006, Spain

  • Hospital Universitario de Leon

    León, 24071, Spain

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