A simple drink may help seniors rebuild strength after illness
NCT ID NCT07753239
First seen Aug 07, 2026 · Last updated Aug 07, 2026
Summary
This trial tests whether adding a twice-daily nutritional drink to standard care helps adults aged 55 and older regain weight and muscle strength after being hospitalized for an acute illness. Participants are at risk of malnutrition and have low grip strength. Half receive the drink plus dietary counseling and activity advice; the other half receive only the counseling and advice. The study tracks changes in weight, muscle strength, physical function, and overall nutritional status over 180 days.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- an oral nutritional supplement (ONS) drink taken twice daily
- What this could lead to
- If effective, this could offer a simple, at-home way to help older adults recover weight and muscle strength after an acute illness, potentially reducing frailty and improving independence.
- What could go wrong
- The trial is relatively small and early, and results may not apply to everyone. The supplement may cause digestive discomfort, and benefits might be modest compared with standard care alone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 304 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
-
Oct 2026
An estimate. Start dates often move.
- Expected to finish
-
Jan 2028
An estimate. End dates often move.
- Lead sponsor
-
A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
55 to 99 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. At risk of malnutrition. 2. At the point of hospital discharge, the admission was for an acute medical illness. 3. Has low maximum handgrip strength. 4. Estimated life expectancy of more than 12 months. 5. Community ambulant. 6. No other chronic disease. 7. Able to communicate and follow instructions. 8. Able to consume food and beverages orally. 9. Willing to refrain from taking non-study oral nutritional supplements over the course of the study. 10. Able and willing to follow study procedures. Exclusion Criteria: 1. Index hospitalization admission was for a surgical procedure or a stroke/myocardial infarction. 2. Diagnosed with type 1 or type 2 diabetes. 3. Has an active infectious disease. 4. Diagnosed with severe gastrointestinal disorders. 5. With severe or unstable congestive heart failure. 6. With chronic kidney disease stage 2 or higher, end-stage organ failure, or other pre-terminal condition. 7. Has an active malignancy within the past five years or currently receiving treatment for malignancy. 8. Has a severe or unstable musculoskeletal or neuromuscular disorder. 9. Unable to perform a valid handgrip strength assessment. 10. Any condition that makes the participant unsuitable for the study. 11. Currently enrolled in another clinical study. 12. Has an eating disorder, alcoholism or substance abuse. 13. Has dementia, delirium, or a significant neurological or psychiatric disorder. 14. Known allergy or intolerance to any ingredients of the study product. 15. Continuous use of ONS for 14 days prior to the baseline visit. 16. Has used herbal products, dietary supplements, or medications in the past 30 days that could affect body weight, appetite, or body composition. 17. Presence of clinically significant ascites, pleural effusion, edema, or dehydration.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Low muscle strength are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
7 sites. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
King Chulalongkorn Memorial Hospital
Bangkok, Thailand
-
Maharaj Nakorn Chiang Mai Hospital
Chiang Mai, Thailand
-
Naresuan University Hospital
Phitsanulok, Thailand
-
Phramongkutklao Hospital
Bangkok, Thailand
-
Siriraj Hospital
Bangkok, Thailand
-
Songklanagarind Hospital
Hat Yai, Thailand
-
Vajira Hospital
Bangkok, Thailand
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Four-Part check may reveal hidden malnutrition in sickest kids
- Can protein shakes help older veterans bounce back after surgery?
- Why do some malnourished infants recover and others Don't? hospitals track every gram
- Can IV nutrition at an outpatient clinic help malnourished surgery patients?
- Searching for biomarkers to combat malnutrition
- One diet plan to fight two forms of malnutrition in kids?