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Can a smartphone app help rural cancer patients beat the odds?

NCT ID NCT05221606

Symptom relief Sponsor: University of Pittsburgh Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests an electronic symptom management system called Nurse AMIE in 344 people with stage 3 or 4 cancer living in rural areas. The goal is to see if using the system helps them live longer and improves their quality of life. Participants use the system to report symptoms and get support, and researchers track survival and well-being over time.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 344 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2022

Expected to finish

Mar 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Patient receiving care for their cancer 2. Age: 18+ years of age 3. Has stage 3 or 4 cancer, or an unstaged cancer that is considered 'advanced' (greater than stage 2) by their treating oncologist 4. Must be within six months of initiation of pharmacologic or radiation treatment, for curative or palliative purposes, from a medical or radiation oncologist 5. Clinician-rated ECOG function of 0-3 6. Lives in a county with RUCC code 4 - 9 and/or zip code with RUCA code 4-10 7. Has access to personal device capable of receiving telephone calls for study facilitator check-ins 8. Fluent in written and spoken English 9. Sufficient vision/hearing to interact with the tablet and study staff 10. Clinician-defined life expectancy of 6 months or more Exclusion Criteria: 1. Patients with medical or psychiatric conditions documented in the medical record (beyond cancer, its treatments, and its symptoms) that would impair our ability to test study hypotheses (e.g. psychotic disorders, dementia, inability to give informed consent, or follow study instructions). 2. Patients who are participating in any other supportive care or behavioral intervention studies. 3. Non-English speaking patients will be excluded, as they represent less than 2% of the population targeted.

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Conditions

The condition(s) this trial relates to.

cancer Motor Activity neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cancer

Contacts and locations

Locations

  • Mount Nittany Medical Center

    State College, Pennsylvania, 16803, United States

  • Penn State Hershey Medical Center

    Hershey, Pennsylvania, 17033, United States

  • UPMC - Greenville

    Greenville, Pennsylvania, 16125, United States

  • UPMC - Indiana

    Indiana, Pennsylvania, 15701, United States

  • UPMC - New Castle

    New Castle, Pennsylvania, 16105, United States

  • UPMC - Northwest

    Seneca, Pennsylvania, 16346, United States

  • UPMC-Butler

    Butler, Pennsylvania, 16001, United States

  • West Virginia University

    Morgantown, West Virginia, 26506, United States

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