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Blood test may predict heart attack risk during surgery

NCT ID NCT04014647

Knowledge-focused Sponsor: Norfolk and Norwich University Hospitals NHS Foundation Trust Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is looking at whether a blood test called NT-proBNP can help predict serious problems like heart attacks or death in people having vascular surgery. Researchers will measure this marker before and after surgery in 200 patients. The goal is to see if the test can identify who is at higher risk, so doctors can take extra precautions.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could lead to a simple blood test that helps doctors identify high-risk patients before vascular surgery, potentially reducing complications.
What could go wrong
This is an early observational study with only 200 participants, so results may not apply to all patients. The test may not reliably predict outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 200 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2019

Expected to finish

Sep 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients who have been referred to have vascular surgery

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients who are equal to or over 18 years old * Patients scheduled to undergo elective surgery for the following procedures: * Infrainguinal arterial reconstruction * Aortic aneurysm * Aorto-bifemoral bypass / or aortic endarterectomy * Femoro-popliteal bypass * Femoro-distal bypass * Femoral endarterectomy * Femoro-femoral crossover * Axillo-femoral bypass * Elective carotid surgery * Patients having either general or regional anaesthesia for their surgery Exclusion Criteria:- * Patients undergoing emergency surgery * Those who are unable or unwilling to give informed consent * Patients with unstable coronary syndromes (acute or recent MI with evidence of important ischemic risk by clinical symptoms or stress testing or unstable or severe angina pectoris) * Patients with decompensated heart failure (new onset shortness of breath and rales together with echocardiographic evidence of cardiac dysfunction or deterioration of chronic heart failure despite heart failure therapy) * Patients with chronic atrial fibrillation

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Conditions

The condition(s) this trial relates to.

aortic aneurysm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Vascular surgical procedure

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Norfolk & Norwich University Hospitals NHS Foundation Trust

    RECRUITING

    Norwich, Norfolk, NR4 7UY, United Kingdom

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