Toothbrush vibration could fix fused teeth, tiny study hints
NCT ID NCT05695105
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tested two new methods to treat dental ankylosis, a condition where a tooth fuses to the jawbone, stopping normal growth. Five people aged 6 to 30 received either electric toothbrush vibration or mini-implant-assisted force to move the affected tooth. Researchers measured changes in tooth position and bone levels over 9 months to see if these treatments could help.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Electric toothbrush-generated vibration and mini-implant-assisted orthodontic treatment
- What this could lead to
- If successful, this could offer a new, less invasive way to treat dental ankylosis and reduce bone defects in affected teeth.
- What could go wrong
- This is a very small, early study with only 5 participants and no control group. Results may not apply to everyone, and the treatments may not work as hoped.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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5 people
The number who actually took part.
- Started
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Jul 2023
- Finished
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Dec 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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6 to 30 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Full informed consent and/or informed assent (minors) * Be willing and able to comply with all study requirements * Male or female * Aged 6-30 * Clinically diagnosed to have either an ankylosed deciduous tooth or a non-third molar mildly- to moderately- ankylosed permanent tooth, and with crown partially visible in the oral cavity. Clinical diagnosis of ankylosis includes the following factors: dental trauma history, infra-eruption with no apparent mechanical obstruction or other cause, contralateral tooth in occlusal contact for over one year, decreased alveolar bone height, no or reduced tooth mobility, and x-ray or cone-beam computer tomography (CBCT) imaging indications of an obliterated PDL space. Ultimately, the diagnosis will be confirmed by lack of tooth movement discovered during orthodontic treatment or when subjected to a heavy force through our study (Phelan M K, et al. 1990). * English speaking (primary language or fluent) Exclusion Criteria: * Severe and extensive ankylosis of permanent teeth as diagnosed through CBCT * Primary failure of eruption with previous orthodontic treatment * Any systemic disorders particularly those affecting bleeding or skeletal health * Any systemic medications * Any mental or developmental disorders that affect patient understanding or compliance * Allergic to our local anesthetic drug * Can pass an infectious disease to someone else right now (e.g., having a flu) * Is pregnant * Has a history of smoking * Have not reached the age of 6 or older than age of 30 * Not cooperative enough during dental examinations * The dentist finds out that he/she is not able to keep the mini-implant, the brackets and the wires in place around the tooth that is being treated * Not fluent in English
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Rutgers School of Dental Medicine
Newark, New Jersey, 07103, United States