Minty colonoscopy rinse could boost cancer detection
NCT ID NCT07501975
First seen Jun 24, 2026 · Last updated Jun 24, 2026
Summary
This trial tests a special rinse solution containing menthol (from peppermint) and simethicone (a defoamer) during colonoscopy. The goal is to reduce muscle spasms and clear bubbles, giving doctors a better view to find precancerous polyps. About 500 adults undergoing colonoscopy will be randomly assigned to get the new rinse or standard saline. The main measure is how many polyps are found.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
0.1% menthol solution combined with simethicone aqueous suspension
What this could lead to
If it works, this could make colonoscopies more comfortable and effective at finding polyps, potentially improving early cancer detection.
What could go wrong
This is an early-stage trial with no phase designation, so results are uncertain. The solution may not significantly improve detection or could cause unexpected side effects.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.