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Healthy volunteers needed to define normal heart and lung function

NCT ID NCT07641413

Knowledge-focused Sponsor: University of California, San Francisco Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Sep 15, 2026 · Updated 2 times

Summary

This study aims to establish normal reference values for heart and lung function in healthy adults aged 24-68. Researchers will perform breathing tests, exercise tests, and heart ultrasounds on 200 participants without known lung or heart disease. The results will serve as a comparison for veterans who may have been exposed to airborne hazards during military service.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 200 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2024

Expected to finish

Dec 2030

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Healthy "normal" adults within the age range relevant to the United States Veteran population who served in the Southwest Asia theater of military operations.

Ages

24 to 68 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 24-68 * U.S. Veteran deployed between 1990 to 2021 * No respiratory complaints (defined as modified Medical Research Council score = 0) * No use of respiratory medications Exclusion Criteria: * Non-English speaking * Pregnancy * BMI\>35 Kg/m2 * Tobacco smoking within prior year * Lifetime tobacco smoking of \>5 pack-years * Current inhaled cannabis use (any modality) \>2x weekly * Prior inhaled cannabis uses exceeding 2x weekly within the prior year * Illicit drug use (other than cannabis) * No prior or current major organ disease, including but not limited to: * Neuromuscular weakness * History of malignancy (other than non-melanoma skin cancer)-- HIV/AIDS * Autoimmune disease * Solid-organ or hematopoietic stem cell transplant * Cardiovascular disease (other than mild HTN; \< 140/90; controlled on 2 or less medications) * Poorly-controlled HTN (SBP\>140 or DBP\>90 or use of more than 2 anti-hypertensive medications) * Any history of congestive heart failure (CHF, either HFpEF or HFrEF) * Any history of arrythmia (including atrial fibrillation)

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Conditions

The condition(s) this trial relates to.

Dyspnea

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cardiopulmonary Dyspnea Pollution related respiratory disorder Pollution; exposure

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • University of California San Francisco

    RECRUITING

    San Francisco, California, 94143, United States

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