What's normal for a Child's esophagus? a new study aims to find out
NCT ID NCT07754695
First seen Aug 10, 2026 · Last updated Sep 09, 2026 · Updated 3 times
Summary
This study aims to measure the normal flexibility (distensibility) of the esophagus in children aged 5 to 17 who are already undergoing anesthesia for a clinically indicated colonoscopy. Using a device called EndoFLIP, researchers will take quick measurements of the esophagus before the scheduled procedure. The goal is to establish preliminary reference values for esophageal distensibility in healthy children, which could help doctors better evaluate and manage esophageal disorders in the future.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Endoluminal Functional Lumen Imaging Probe (EndoFLIP) - a device that measures esophageal dimensions and pressure during a brief procedure under anesthesia.
- What this could lead to
- If successful, this could establish normal reference values for esophageal flexibility in children, improving diagnosis and evaluation of esophageal disorders.
- What could go wrong
- This is a small, early-stage study focused on healthy children, so results may not apply to all populations. The procedure is brief but invasive, requiring anesthesia.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
-
Oct 2026
An estimate. Start dates often move.
- Expected to finish
-
Sep 2028
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
5 to 17 years
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 5 to \<18 years * Scheduled to undergo clinically indicated colonoscopy with colonic motility catheter placement under general anesthesia * No upper gastrointestinal symptoms (including dysphagia, recurrent vomiting, gastroesophageal reflux, or odynophagia) * No history of esophageal disease or esophageal surgery * Parent/guardian consent and participant assent, when applicable Exclusion Criteria: * Known or suspected esophageal pathology * Prior esophageal surgery or instrumentation * Anatomic upper gastrointestinal abnormalities * Contraindication to anesthesia or EndoFLIP catheter placement
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Normal esophageal distensibility are added.
Genom att skicka in godkänner du våra Användarvillkor
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.