New imaging study aims to sharpen diagnosis of skin lesions without a biopsy
NCT ID NCT04743362
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is testing whether noninvasive imaging methods can help doctors diagnose skin and mouth lesions more accurately before deciding on a biopsy. Researchers will collect images from up to 5,010 participants, including healthy volunteers and patients with lesions, using a special camera that provides detailed pictures of the skin. The goal is to build a database of images to support clinical care, teaching, and future research.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 5,010 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Feb 2021
- Expected to finish
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Aug 2031
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
For this study, we anticipate to recruit \~5000 participants over a period of 7 years. Of this, \~4000 will be patients with a muco-cutaneous lesion and \~1000 will be volunteers. Patients in the Dermatology, Clinical Immunology Services, Pediatrics, Bone Marrow Transplant, Dental, and Radiation Oncology departments who have a muco-cutaneous lesion/process amenable to imaging with one or more of the available noninvasive devices will be offered the opportunity to participate in the study. In addition to patients and volunteers, MSK clinicians will be recruited to the study via clinician verbal informed consent.
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * All ages * Patients with a muco-cutaneous lesion(s) amenable to imaging by non-invasive tools * Healthy volunteer subjects * Ability to give informed consent or in the case of pediatric patients, assent and consent from the parent/guardian Exclusion Criteria: * Allergy or intolerance to ultrasound gel or mineral oil used for imaging * Patients who are not able to comply with imaging procedure
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Memorial Sloan Kettering Cancer Center (All Protocol Activities)
RECRUITINGNew York, New York, 10065, United States
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