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Simple skin test may spare women from invasive heart procedures

NCT ID NCT07558018

Diagnosis Sponsor: National Institute of Cardiology, Laranjeiras, Brazil Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a noninvasive skin test can accurately diagnose microvascular heart problems in women who have chest pain but clear major arteries. Researchers will compare skin blood vessel function with invasive heart measurements in 60 women. If the skin test works, it could replace risky catheter procedures for many patients.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could lead to a simple, noninvasive way to diagnose microvascular heart problems in women, avoiding risky catheter procedures.
What could go wrong
This is a small, early-stage study (60 people) that hasn't started recruiting yet. The skin test may not accurately reflect heart blood vessel function, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Aug 2026

An estimate. Start dates often move.

Expected to finish

Dec 2029

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients from a terciary cardiology hospital.

Ages

18 to 65 years

Sex

Female participants only

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18-65 years * Anginal chest pain Exclusion Criteria: * Malignant neoplasms * Autoimmune diseases * Acute systemic diseases * Pregnancy or lactation * Iodine allergy * CAD on invasive coronary angiography or coronary computed tomography angiography (CCTA)

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Conditions

The condition(s) this trial relates to.

coronary microvascular disorder Microvascular Angina

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Angina, microvascular

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  2. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.